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Herstellung und Charakterisierung von dreidimensionalen Mikrostrukturen für Zellexperimente

Striebel, Thomas

Abstract:
Adhesion of tissue cells is traditionally studied on flat substrates. However, much less is known about how cells behave in three-dimensional environments. We apply direct laser writing to design three-dimensional scaffolds. By using different photoresists, we were able to vary the stiffness of the scaffolds, to optimize the system for imaging and to define the contact sites cells build up. Using quantitative image processing, we analyzed shape, traction and adhesion structures of cells.

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Volltext §
DOI: 10.5445/IR/1000023387
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Angewandte Physik (APH)
Institut für Nanotechnologie (INT)
Publikationstyp Hochschulschrift
Publikationsjahr 2011
Sprache Deutsch
Identifikator urn:nbn:de:swb:90-233878
KITopen-ID: 1000023387
HGF-Programm 43.14.01 (POF II, LK 01) Photonics crystals and metamaterials
Verlag Karlsruher Institut für Technologie (KIT)
Art der Arbeit Dissertation
Fakultät Fakultät für Physik (PHYSIK)
Institut Institut für Angewandte Physik (APH)
Prüfungsdaten 13.05.2011
Referent/Betreuer Prof. M. Wegener
Schlagwörter Direct Laser Writing, Microstructures, Surface Functionalisation, Cell Biology
KIT – Die Forschungsuniversität in der Helmholtz-Gemeinschaft
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