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URN: urn:nbn:de:swb:90-233878

Herstellung und Charakterisierung von dreidimensionalen Mikrostrukturen für Zellexperimente

Striebel, Thomas

Abstract:
Adhesion of tissue cells is traditionally studied on flat substrates. However, much less is known about how cells behave in three-dimensional environments. We apply direct laser writing to design three-dimensional scaffolds. By using different photoresists, we were able to vary the stiffness of the scaffolds, to optimize the system for imaging and to define the contact sites cells build up. Using quantitative image processing, we analyzed shape, traction and adhesion structures of cells.


Zugehörige Institution(en) am KIT Institut für Angewandte Physik (APH)
Institut für Nanotechnologie (INT)
Publikationstyp Hochschulschrift
Jahr 2011
Sprache Deutsch
Identifikator KITopen ID: 1000023387
HGF-Programm 43.14.01; LK 01
Verlag Karlsruhe
Abschlussart Dissertation
Fakultät Fakultät für Physik (PHYSIK)
Institut Institut für Angewandte Physik (APH)
Prüfungsdaten 13.05.2011
Referent/Betreuer Prof. M. Wegener
Schlagworte Direct Laser Writing, Microstructures, Surface Functionalisation, Cell Biology
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