KIT | KIT-Bibliothek | Impressum
Open Access Logo
§
Volltext
URN: urn:nbn:de:swb:90-303892

Aqueous two phase extraction of proteins: From molecular understanding to process development

Oelmeier, Stefan A.

Abstract:
A high throughput screening method was implemented and applied to an industrial separation task. Previously reported correlations between protein descriptors and distribution were evaluated. A new approach to screen ATPS for their industrial application was devised and put to use for the selection of ATPSs used in centrifugal partitioning chromatography. A new modeling approach based on molecular dynamics was set up. This approach was validated using single PEG molecules in solution.


Zugehörige Institution(en) am KIT Institut für Bio- und Lebensmitteltechnik (BLT)
Publikationstyp Hochschulschrift
Jahr 2012
Sprache Englisch
Identifikator KITopen ID: 1000030389
Verlag Karlsruhe
Abschlussart Dissertation
Fakultät Fakultät für Chemieingenieurwesen und Verfahrenstechnik (CIW)
Institut Institut für Bio- und Lebensmitteltechnik (BLT)
Prüfungsdaten 28.09.2012
Referent/Betreuer Prof. J. Hubbuch
KIT – Die Forschungsuniversität in der Helmholtz-Gemeinschaft KITopen Landing Page