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Phylogeny-Aware Placement and Alignment Methods for Short Reads

Berger, Simon A.

In recent years bioinformatics has entered a new phase: New sequencing methods, generally referred to as Next Generation Sequencing (NGS) have become widely available. This thesis introduces algorithms for phylogeny aware analysis of short sequence reads, as generated by NGS methods in the context of metagenomic studies. A considerable part of this work focuses on the technical (w.r.t. performance) challenges of these new algorithms, which have been developed specifically to exploit parallelism.

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DOI: 10.5445/IR/1000033893
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Theoretische Informatik (ITI)
Publikationstyp Hochschulschrift
Publikationsjahr 2013
Sprache Englisch
Identifikator urn:nbn:de:swb:90-338935
KITopen-ID: 1000033893
Verlag Karlsruher Institut für Technologie (KIT)
Art der Arbeit Dissertation
Fakultät Fakultät für Informatik (INFORMATIK)
Institut Institut für Theoretische Informatik (ITI)
Prüfungsdaten 14.01.2013
Referent/Betreuer Prof. A. Stamatakis
Schlagwörter short-read alignment parallel phylogeny
KIT – Die Forschungsuniversität in der Helmholtz-Gemeinschaft
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