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Postprint
DOI: 10.5445/IR/1000038638
Veröffentlicht am 19.07.2018
Originalveröffentlichung
DOI: 10.1155/2012/541471
Scopus
Zitationen: 30

Hydrogen Peroxide in Inflammation : Messenger, Guide, and Assassin

Wittmann, C.; Chockley, P.; Singh, S. K.; Pase, L.; Lieschke, G. J.; Grabher, C.

Abstract:
Starting as a model for developmental genetics, embryology, and organogenesis, the zebrafish has become increasingly popular as a model organism for numerous areas of biology and biomedicine over the last decades.Within haematology, this includes studies on blood cell development and function and the intricate regulatory mechanisms within vertebrate immunity. Here, we review recent studies on the immediate mechanisms mounting an inflammatory response by in vivo analyses using the zebrafish. These recently revealed novel roles of the reactive oxygen species hydrogen peroxide that have changed our view on the initiation of a granulocytic inflammatory response.


Zugehörige Institution(en) am KIT Institut für Toxikologie und Genetik (ITG)
Publikationstyp Zeitschriftenaufsatz
Jahr 2012
Sprache Englisch
Identifikator ISSN: 1687-9104, 1687-9112
URN: urn:nbn:de:swb:90-386384
KITopen ID: 1000038638
HGF-Programm 47.01.01; LK 01
Erschienen in Advances in hematology
Heft 1
Seiten Art.Nr. 541471
Bemerkung zur Veröffentlichung Gefördert durch den KIT-Publikationsfonds
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