This proceedings document the 2nd Annual Workshop of the EURATOM FP7 Collaborative Project FIRST-Nuclides (Fast / Instant Release of Safety Relevant Radionuclides from Spent Nuclear Fuel). 10 beneficiaries and 11 associated groups participated in the 2nd Annual Workshop, as well as interested externals. The key purpose of the proceedings is documenting the scientific outcome of the FIRST-Nuclides project. This is covered by scientific/technical contributions of the partners. It includes reports by the Associated Groups and the Topical Session.