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URN: urn:nbn:de:swb:90-432495
DOI: 10.1155/2014/251814
Zitationen: 5
Web of Science
Zitationen: 2

Optical coherence tomography guided laser cochleostomy: towards the accuracy on tens of micrometer scale

Zhang, Y.; Pfeiffer, T.; Weller, M.; Huber, R.; Raczkowsky, J.; Schipper, J.; Wörn, H.; Klenzner, T.

Lasers have been proven to be precise tools for bone ablation. Applying no mechanical stress to the patient, they are potentially very suitable for microsurgery on fragile structures such as the inner ear. However, it remains challenging to control the laser-bone ablation without injuring embedded soft tissue. In this work, we demonstrate a closed-loop control of a short-pulsed CO2 laser to perform laser cochleostomy under the monitoring of an optical coherence tomography (OCT) system. A foresighted detection of the bone-endosteum-perilymph boundary several hundred micrometers before its exposure has been realized. Position and duration of the laser pulses are planned based on the residual bone thickness distribution. OCT itself is also used as a highly accurate tracking system for motion compensation between the target area and the optics. During ex vivo experimental evaluation on fresh porcine cochleae, the ablation process terminated automatically when the thickness of the residual tissue layer uniformly reached a predefined value. The shape of the resulting channel bottom converged to the natural curvature of the endosteal layer ... mehr

Zugehörige Institution(en) am KIT Institut für Anthropomatik und Robotik (IAR)
Publikationstyp Zeitschriftenaufsatz
Jahr 2014
Sprache Englisch
Identifikator ISSN: 2314-6133
KITopen ID: 1000043249
Erschienen in BioMed Research International
Band 2014
Seiten 251814
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