KIT | KIT-Bibliothek | Impressum | Datenschutz

All-Atom Modeling of Protein Folding and Aggregation

Wolf, Moritz

Abstract:
Theoretical investigations of biorelevant processes in the life-science research require highly optimized simulation methods. Therefore, massively parallel Monte Carlo algorithms, namely MTM, were successfully developed and applied to the field of reversible protein folding allowing the thermodynamic characterization of proteins on an atomistic level. Further, the formation process of trans-membrane pores in the TatA system could be elucidated and the structure of the complex could be predicted.

Open Access Logo


Volltext §
DOI: 10.5445/IR/1000043285
Seitenaufrufe: 16
seit 07.05.2018
Downloads: 60
seit 23.09.2014
Zugehörige Institution(en) am KIT Institut für Nanotechnologie (INT)
Publikationstyp Hochschulschrift
Jahr 2013
Sprache Englisch
Identifikator urn:nbn:de:swb:90-432853
KITopen-ID: 1000043285
HGF-Programm 43.11.03 (POF II, LK 01)
Verlag KIT, Karlsruhe
Abschlussart Dissertation
Fakultät Fakultät für Physik (PHYSIK)
Institut Institut für Nanotechnologie (INT)
Prüfungsdaten 22.11.2013
Referent/Betreuer Prof. W. Wenzel
Schlagworte Reversible protein folding, MTM, Twin arginine translocase, TatA, SIMONA
KIT – Die Forschungsuniversität in der Helmholtz-Gemeinschaft
KITopen Landing Page