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Micro- and Nanostructured Microfluidic Devices for Localized Protein Immobilization and Other Biomedical Applications

Steidle, Nicole E.

A new immobilization method for the localized adsorption of proteins on thermoplastic surfaces is introduced. Artificial three-phase interfaces were realized by surface structuring to control the wetting behavior which lead to a preferred adsorption in these modified areas. Additionally, different fabrication methods were analyzed to determine mass fabrication capabilities. These fabrication methods also allowed the production of fully structured microchannels to tune the fluids behavior within.

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Volltext §
DOI: 10.5445/IR/1000043695
Zugehörige Institution(en) am KIT Institut für Mikrostrukturtechnik (IMT)
Publikationstyp Hochschulschrift
Jahr 2014
Sprache Englisch
Identifikator urn:nbn:de:swb:90-436953
KITopen-ID: 1000043695
Verlag KIT, Karlsruhe
Abschlussart Dissertation
Fakultät Fakultät für Maschinenbau (MACH)
Institut Institut für Mikrostrukturtechnik (IMT)
Prüfungsdaten 24.06.2014
Referent/Betreuer Prof. A. E. Gruber
Schlagworte Mikrotechnik, Lab-on-a-Chip, Replikation, Heißprägen
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KIT – Die Forschungsuniversität in der Helmholtz-Gemeinschaft
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