KIT | KIT-Bibliothek | Impressum | Datenschutz

Rhamnolipids as biosurfactants from renewable resources: concepts for next-generation rhamnolipid production

Henkel, Marius 1; Müller, Markus M. 1; Kügler, Johannes H. 1; Lovaglio, Roberta B.; Contiero, Jonas; Syldatk, Christoph 1; Hausmann, Rudolf
1 Institut für Bio- und Lebensmitteltechnik (BLT), Karlsruher Institut für Technologie (KIT)


Several microorganisms are known to produce a wide variety of surface-active substances, which are referred to as biosurfactants. Interesting examples for biosurfactants are rhamnolipids, glycolipids mainly known from Pseudomonas aeruginosa produced during cultivation on different substrates like vegetable oils, sugars, glycerol or hydrocarbons. However, besides costs for downstream processing of rhamnolipids, relatively high raw-material prices and low productivities currently inhibit potential economical production of rhamnolipids on an industrial scale. This review focuses on cost-effective and sustainable production of rhamnolipids by introducing new possibilities and strategies regarding renewable substrates. Additionally, past and recent production strategies using alternative substrates such as agro-industrial byproducts or wastes are summarized. Requirements and concepts for next-generation rhamnolipid producing strains are discussed and potential targets for strain-engineering are presented. The discussion of potential new strategies is supported by an analysis of the metabolism of different Pseudomonas species. According to calculations of theoretical substrate-to-product conversion yields and current world-market price analysis, different renewable substrates are compared and discussed from an economical point of view. ... mehr

DOI: 10.1016/j.procbio.2012.04.018
Zitationen: 197
Web of Science
Zitationen: 167
Zitationen: 202
Zugehörige Institution(en) am KIT Institut für Bio- und Lebensmitteltechnik (BLT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2012
Sprache Englisch
Identifikator ISSN: 1359-5113
KITopen-ID: 1000049404
Erschienen in Process Biochemistry
Verlag Elsevier
Band 47
Heft 8
Seiten 1207-1219
Nachgewiesen in Dimensions
Web of Science
KIT – Die Forschungsuniversität in der Helmholtz-Gemeinschaft
KITopen Landing Page