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DOI: 10.5445/IR/1000052082

Characterization, Manipulation, and Prediction of Protein Aggregation in Model Systems

Galm, Lara

Abstract:
Main influencing factors favoring protein aggregation are to be identified regarding solution conditions of the surrounding aqueous solution and regarding physicochemical properties of the model proteins themselves. Based on these experimental results, concepts are developed for manipulation of protein aggregation behavior. Finally, based on selected parameters that significantly impact protein aggregation behavior, approaches are developed to predict protein aggregation propensity.


Zugehörige Institution(en) am KIT Institut für Bio- und Lebensmitteltechnik (BLT)
Publikationstyp Hochschulschrift
Jahr 2015
Sprache Englisch
Identifikator URN: urn:nbn:de:swb:90-520821
KITopen ID: 1000052082
Verlag Karlsruhe
Abschlussart Dissertation
Fakultät Fakultät für Chemieingenieurwesen und Verfahrenstechnik (CIW)
Institut Institut für Bio- und Lebensmitteltechnik (BLT)
Prüfungsdaten 18.12.2015
Referent/Betreuer Prof. J. Hubbuch
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