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DOI: 10.5445/IR/1000052759

Characterization of microtubule organizing center associated proteins in Aspergillus nidulans

Zhang, Ying

Abstract:
In A.nidulans, MT polymerization is initiated at sMTOCs and not only from nuclear SPBs. SPA18 directly binds to ApsB at SPBs and sMTOCs, forming an ApsB/SPA18 complex which is required for recruitment of γ-TuRCs. ApsB and SPA18 are targeted to sMTOC by SPA10, to the OP of SPBs by SepK. MztA is a γ-TuRC protein. PcpA is the γ-TuRC receptor at the IP of SPB. SfiA is essential for SPB duplication. All of the findings suggest only the outer plaque of SPB locates at the sMTOC.


Zugehörige Institution(en) am KIT Institut für Angewandte Biowissenschaften (IAB)
Publikationstyp Hochschulschrift
Jahr 2015
Sprache Englisch
Identifikator URN: urn:nbn:de:swb:90-527593
KITopen-ID: 1000052759
Verlag Karlsruhe
Abschlussart Dissertation
Fakultät Fakultät für Chemie und Biowissenschaften (CHEM-BIO)
Institut Institut für Angewandte Biowissenschaften (IAB)
Prüfungsdaten 18.12.2015
Referent/Betreuer Prof. R. Fischer
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