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Tacky cyclic olefin copolymer: a biocompatible bonding technique for the fabrication of microfluidic channels in COC

Keller, Nico; Nargang, Tobias M.; Runck, Matthias; Kotz, Frederik; Striegel, Andreas; Sachsenheimer, Kai; Klemm, Denis; Lange, Kerstin; Worgull, Matthias; Richter, Christiane; Helmer, Dorothea; Rapp, Bastian E.

Abstract: Cyclic olefin copolymer (COC) is widely used in microfluidics due to its UV-transparency{,} its biocompatibility and high chemical resistance. Here we present a fast and cost-effective solvent bonding technique{,} which allows for the efficient bonding of protein-patterned COC structures. The bonding process is carried out at room temperature and takes less than three minutes. Enzyme activity is retained upon bonding and microstructure deformation does not occur.


Zugehörige Institution(en) am KIT Institut für Mikrostrukturtechnik (IMT)
Karlsruhe Nano Micro Facility (KNMF)
Publikationstyp Zeitschriftenaufsatz
Jahr 2016
Sprache Englisch
Identifikator DOI: 10.1039/C5LC01498K
ISSN: 1473-0189, 1473-0197
URN: urn:nbn:de:swb:90-545171
KITopen ID: 1000054517
HGF-Programm 47.02.07; LK 01
Erschienen in Lab on a chip
Band 16
Heft 9
Seiten 1561-1564
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