KIT | KIT-Bibliothek | Impressum | Datenschutz
Open Access Logo
§
Volltext
URN: urn:nbn:de:swb:90-552744
Originalveröffentlichung
DOI: 10.3762/bjnano.6.145
Scopus
Zitationen: 20
Web of Science
Zitationen: 18

Peptide-equipped tobacco mosaic virus templates for selective and controllable biomineral deposition

Altintoprak, Klara; Seidenstuecker, Axel; Welle, Alexander; Eiben, Sabine; Atanasova, Petia; Stitz, Nina; Plettl, Alfred; Bill, Joachim; Gliemann, Hartmut; Jeske, Holger; Rothenstein, Dirk; Geiger, Fania; Wege, Christina

Abstract:
The coating of regular-shaped, readily available nanorod biotemplates with inorganic compounds has attracted increasing interest during recent years. The goal is an effective, bioinspired fabrication of fiber-reinforced composites and robust, miniaturized technical devices. Major challenges in the synthesis of applicable mineralized nanorods lie in selectivity and adjustability of the inorganic material deposited on the biological, rod-shaped backbones, with respect to thickness and surface profile of the resulting coating, as well as the avoidance of aggregation into extended superstructures. Nanotubular tobacco mosaic virus (TMV) templates have proved particularly suitable towards this goal: Their multivalent protein coating can be modified by high-surface-density conjugation of peptides, inducing and governing silica deposition from precursor solutions in vitro. In this study, TMV has been equipped with mineralization-directing peptides designed to yield silica coatings in a reliable and predictable manner via precipitation from tetraethoxysilane (TEOS) precursors. Three peptide groups were compared regarding their influence on s ... mehr


Zugehörige Institution(en) am KIT Institut für Biologische Grenzflächen (IBG)
Center for Functional Nanostructures (CFN)
Institut für Angewandte Physik (APH)
Institut für Funktionelle Grenzflächen (IFG)
Karlsruhe Nano Micro Facility (KNMF)
Publikationstyp Zeitschriftenaufsatz
Jahr 2015
Sprache Englisch
Identifikator ISSN: 2190-4286
KITopen ID: 1000055274
HGF-Programm 49.02; LK 02
Erschienen in Beilstein journal of nanotechnology
Band 6
Heft 1
Seiten 1399-1412
Bemerkung zur Veröffentlichung Attribution 2.0 Generic (CC BY 2.0)
Schlagworte biomineralization, charge-relay system, peptide; silica, tobacco mosaic virus (TMV)
KIT – Die Forschungsuniversität in der Helmholtz-Gemeinschaft KITopen Landing Page