KIT | KIT-Bibliothek | Impressum | Datenschutz

Effects of dietary milk- and soy phospholipids on lipid-parameters and other risk indicators for cardiovascular diseases in overweight or obese men : two double-blind, randomised, controlled, clinical trials

Weiland, Anne; Bub, Achim; Barth, Stephan W.; Schrezenmeir, Jürgen; Pfeuffer, Maria

The present study examined the effect of milk phospholipids (milk-PL) on lipid metabolism and on other risk factors for CVD, in comparison with milk fat (control) or soya phospholipids (soya-PL), respectively. Two double-blind parallel-group intervention trials were conducted in overweight or obese male subjects. In the first trial (trial 1), sixty-two men consumed milk enriched with either 2 g milk-PL or 2 g milk fat (control) for 8 weeks. In trial 2, fifty-seven
men consumed milk enriched with either 3 g milk-PL or 2·8 g soya-PL for 7 weeks. In trial 1, milk-PL as compared with control reduced waist circumference but did not affect plasma lipids (total, HDL- and LDL-cholesterol, total cholesterol:HDL-cholesterol ratio, TAG, phospholipids), apoB, apoA1, glucose, insulin, insulin sensitivity index, C-reactive protein, IL-6, soluble intracellular adhesion molecule and total homocysteine (tHcy). Serum activities of
alanine transaminase and aspartate transaminase were not changed. Activity of γ-glutamyl transferase (GGT), a marker of fatty liver, increased in the control but not in the milk-PL group, with a significant intervention effect. ... mehr

Open Access Logo

Volltext §
DOI: 10.5445/IR/1000055935
DOI: 10.1017/jns.2016.9
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Sport und Sportwissenschaft (IfSS)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2016
Sprache Englisch
Identifikator ISSN: 2048-6790
KITopen-ID: 1000055935
Erschienen in Journal of nutritional science
Verlag Cambridge University Press (CUP)
Band 5
Heft e21
Seiten 1-9
Schlagwörter milk phospholipids, soya phospholipids, plasma lipids, human nutrition, CVD
KIT – Die Forschungsuniversität in der Helmholtz-Gemeinschaft
KITopen Landing Page