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Cognitive change is more positively associated with an active lifestyle than with training interventions in older adults at risk of dementia: a controlled interventional clinical trial

Kuester, Olivia C.; Fissler, Patrick; Laptinskaya, Daria; Thurm, Franka; Scharpf, Andrea 1; Woll, Alexander ORCID iD icon 1; Kolassa, Stephan; Kramer, Arthur F.; Elbert, Thomas; Arnim, Christine A. F. von; Kolassa, Iris-Tatjana
1 Institut für Sport und Sportwissenschaft (IfSS), Karlsruher Institut für Technologie (KIT)


Background: While observational studies show that an active lifestyle including cognitive, physical, and social activities is associated with a reduced risk of cognitive decline and dementia, experimental evidence from corresponding training interventions is more inconsistent with less pronounced effects. The aim of this study was to evaluate and compare training- and lifestyle-related changes in cognition. This is the first study investigating these associations within the same time period and sample.
Methods: Fifty-four older adults at risk of dementia were assigned to 10 weeks of physical training, cognitive training, or a matched wait-list control condition. Lifestyle was operationalized as the variety of self-reported cognitive, physical, and social activities before study participation. Cognitive performance was assessed with an extensive test battery prior to and after the intervention period as well as at a 3-month follow-up. Composite cognition measures were obtained by means of a principal component analysis. Training- and lifestyle-related changes in cognition were analyzed using linear mixed effects models. The strength of their association was compared with paired t-tests.
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Volltext §
DOI: 10.5445/IR/1000060071
DOI: 10.1186/s12888-016-1018-z
Zitationen: 33
Web of Science
Zitationen: 29
Zitationen: 37
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Sport und Sportwissenschaft (IfSS)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2016
Sprache Englisch
Identifikator ISSN: 1471-244X
KITopen-ID: 1000060071
Erschienen in BMC psychiatry
Verlag Springer Fachmedien Wiesbaden
Band 16
Heft 1
Seiten Art. Nr.: 315
Schlagwörter Mild cognitive impairment, Alzheimer’s disease, Activity, Active lifestyle, Cognition, Training, Exercise
Nachgewiesen in Dimensions
Web of Science
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