KIT | KIT-Bibliothek | Impressum
Open Access Logo
Originalveröffentlichung
DOI: 10.1016/j.protcy.2017.04.017

Polymer Structures on Surface Acoustic Wave Biosensors

Ritter, F.; Hedrich, J.; Deck, M.; Ludwig, F.; Shakirov, D.; Rapp, B.E.; Länge, K.

Abstract:
The influence of surface structuring on surface acoustic wave (SAW) biosensor signals has been investigated. Polymer structures on the sensor surfaces were applied by lithography or by self-assembling of polystyrene microparticles. In first experiments, structured and unstructured sensors led to similar results in a model affinity assay using streptavidin and biotinylated protein. On the other hand, structuring had a strong effect on SAW sensor signals obtained by protein adsorption on parylene C coated sensors. Depending on the protein, both decreased (albumin, streptavidin) and increased (fibrinogen) signals were observed with structured SAW sensors. Particularly the latter could contribute to facilitated blood analysis in the future.


Zugehörige Institution(en) am KIT Institut für Mikrostrukturtechnik (IMT)
Publikationstyp Zeitschriftenaufsatz
Jahr 2017
Sprache Englisch
Identifikator ISSN: 2212-0173
KITopen ID: 1000072777
HGF-Programm 47.02.07; LK 01
Erschienen in Procedia Technology
Band 27
Seiten 35–36
Bemerkung zur Veröffentlichung 26th Anniversary World Congress on Biosensors, Göteborg, S, May 25-27, 2016
KIT – Die Forschungsuniversität in der Helmholtz-Gemeinschaft KITopen Landing Page