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High Sensitivity Sensors Made of Perforated Waveguides

Awazu, Koichi; Rockstuhl, Carsten; Fujimaki, Makoto; Fukuda, Nobuko; Tominaga, Junji; Komatsubara, Tetsuro; Ikeda, Takahiro; Ohki, Yoshimichi

Sensors based on surface plasmons or waveguide modes are at the focus of interest for applications in biological or environmental chemistry. Waveguide-mode spectra of 1 μm-thick pure and perforated silica films comprising isolated nanometric holes with great aspect ratio were measured before and after adhesion of streptavidin at concentrations of 500 nM. The shift of the angular position for guided modes was nine times higher in perforated films than in bulk films. Capturing of streptavidin in the nanoholes is at the origin of that largely enhanced shift in the angular position as the amplitude of the guided mode in the waveguide perfectly overlaps with the perturbation caused by the molecules. Hence, the device allows for strongly confined modes and their strong perturbation to enable ultra-sensitive sensor applications.

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Verlagsausgabe §
DOI: 10.5445/IR/1000078647
Veröffentlicht am 13.03.2018
DOI: 10.1364/OE.15.002592
Zitationen: 66
Web of Science
Zitationen: 54
Zitationen: 57
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Theoretische Festkörperphysik (TFP)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2007
Sprache Englisch
Identifikator ISSN: 1094-4087
KITopen-ID: 1000078647
Erschienen in Optics express
Verlag The Optical Society of America (OSA)
Band 15
Heft 5
Seiten 2592-2597
Bemerkung zur Veröffentlichung Mentioned in Virtual Journal for Biomedical Optics
Nachgewiesen in Dimensions
Web of Science
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