Due to the evermore rising number of functions, current E/E architectures are more and more a vulnerable source for faults and a barrier to innovation. This situation is aggravated by the integration of new technologies like Vehicle-to-X Communication (V2XC) which form the basis for a large number of future services and applications. At the same time, this “opening” of the E/E architecture to the outside world increases potential for non-deterministic disturbances. In order to overcome the limitations of current E/E architectures, application of new design principles and methodologies is necessary. Platform-based design (PBD) is a promising solution for the development of safety-critical functions, to increase reliability and to reduce development cost. Within this context, we propose a novel extensible tool chain that targets the facilitation of exploration, validation and verification of future V2X-based automotive E/E architectures. The tool chain supports composition of heterogeneous domain-specific models by integrating a heterogeneous modeling tool with a simulation middleware and serves as starting point for the investigation of PBD concepts in the V2X context. ... mehrWe believe that the tool chain can support modeling and validation of future V2X-based E/E architectures. In the final paper, we will evaluate the proposed approach by means of a case study regarding validation capabilities as well as execution performance.