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Verlagsausgabe
DOI: 10.5445/IR/1000082450
Veröffentlicht am 28.04.2018
Originalveröffentlichung
DOI: 10.1038/s41467-018-03784-x
Scopus
Zitationen: 6
Web of Science
Zitationen: 3

Multicomponent reactions provide key molecules for secret communication

Boukis, Andreas C.; Reiter, Kevin; Froelich, Maximiliane; Hofheinz, Dennis; Meier, Michael A. R.

Abstract:
A convenient and inherently more secure communication channel for encoding messages via specifically designed molecular keys is introduced by combining advanced encryption standard cryptography with molecular steganography. The necessary molecular keys require large structural diversity, thus suggesting the application of multicomponent reactions. Herein, the Ugi four-component reaction of perfluorinated acids is utilized to establish an exemplary database consisting of 130 commercially available components. Considering all permutations, this combinatorial approach can unambiguously provide 500,000 molecular keys in only one synthetic procedure per key. The molecular keys are transferred nondigitally and concealed by either adsorption onto paper, coffee, tea or sugar as well as by dissolution in a perfume or in blood. Re-isolation and purification from these disguises is simplified by the perfluorinated sidechains of the molecular keys. High resolution tandem mass spectrometry can unequivocally determine the molecular structure and thus the identity of the key for a subsequent decryption of an encoded message.


Zugehörige Institution(en) am KIT Institut für Nanotechnologie (INT)
Institut für Organische Chemie (IOC)
Institut für Theoretische Informatik (ITI)
Publikationstyp Zeitschriftenaufsatz
Jahr 2018
Sprache Englisch
Identifikator ISSN: 2041-1723
URN: urn:nbn:de:swb:90-824506
KITopen ID: 1000082450
HGF-Programm 43.21.04; LK 01
Erschienen in Nature Communications
Band 9
Seiten Article no 1439
Bemerkung zur Veröffentlichung Gefördert durch den KIT-Publikationsfonds
Schlagworte Chemical libraries; Information technology
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