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Current perspectives on opisthorchiasis control and cholangiocarcinoma detection in southeast asia (Review)

Khuntikeo, N.; Titapun, A.; Loilome, W.; Yongvanit, P.; Thinkhamrop, B.; Chamadol, N.; Boonmars, T.; Nethanomsak, T.; Andrews, R. H.; Petney, T. N.; Sithithaworn, P.

Similar to bile duct cancer or cholangiocarcinoma (CCA) in the western world, opisthorchiasis-associated CCA in Southeast Asia is an aggressive cancer with high mortality rates. It is known to cause a significant health burden in the opisthorchiasis region in Thailand and possibly throughout mainland Southeast. To reduce this health burden, a comprehensive prevention and control program for opisthorchiasis, as well as CCA, is required. In this review, our aim is to provide a brief update of the current situation regarding the natural history of opisthorchiasis and health burden of CCA in Southeast Asia. A comprehensive approach to tackling these issues being implemented in Thailand under the "Cholangiocarcinoma Screening and Care Program" is described. This comprehensive program consists of a three stage prevention and patient care program. The primary prevention component involves opisthorchiasis screening using a new and sensitive urine assay. The secondary prevention component involves screening for CCA and periductal fibrosis, with suspected CCA patients following the protocol for confirmation and appropriate treatment ... mehr

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Verlagsausgabe §
DOI: 10.5445/IR/1000085271
Veröffentlicht am 23.08.2018
DOI: 10.3389/fmed.2018.00117
Zitationen: 2
Seitenaufrufe: 26
seit 01.10.2018
Downloads: 13
seit 04.10.2018
Zugehörige Institution(en) am KIT Zoologisches Institut (ZOO)
Publikationstyp Zeitschriftenaufsatz
Jahr 2018
Sprache Englisch
Identifikator ISSN: 2296-858X
KITopen-ID: 1000085271
Erschienen in Frontiers in medicine
Band 5
Heft APR
Seiten Art. Nr.: 117
Vorab online veröffentlicht am 30.04.2018
Nachgewiesen in Scopus
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