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Electrocardiographic Imaging Using a Spatio-Temporal Basis of Body Surface Potentials - Application to Atrial Ectopic Activity

Schuler, Steffen 1; Wachter, Andreas ORCID iD icon 1; Dössel, Olaf 1
1 Institut für Biomedizinische Technik (IBT), Karlsruher Institut für Technologie (KIT)


Electrocardiographic imaging (ECGI) strongly relies on a priori assumptions and additional information to overcome ill-posedness. The major challenge of obtaining good reconstructions consists in finding ways to add information that effectively restricts the solution space without violating properties of the sought solution. In this work, we attempt to address this problem by constructing a spatio-temporal basis of body surface potentials (BSP) from simulations of many focal excitations. Measured BSPs are projected onto this basis and reconstructions are expressed as linear combinations of corresponding transmembrane voltage (TMV) basis vectors. The novel method was applied to simulations of 100 atrial ectopic foci with three different conduction velocities. Three signal-to-noise ratios (SNR) and bases of six different temporal lengths were considered. Reconstruction quality was evaluated using the spatial correlation coefficient of TMVs as well as estimated local activation times (LAT). The focus localization error was assessed by computing the geodesic distance between true and reconstructed foci. Compared with an optimally parameterized Tikhonov-Greensite method, the BSP basis reconstruction increased the mean TMV correlation by up to 22, 24, and 32% for an SNR of 40, 20, and 0 dB, respectively. ... mehr

Verlagsausgabe §
DOI: 10.5445/IR/1000085656
Veröffentlicht am 12.11.2018
DOI: 10.3389/fphys.2018.01126
Zitationen: 4
Zitationen: 4
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Biomedizinische Technik (IBT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2018
Sprache Englisch
Identifikator ISSN: 1664-042X
KITopen-ID: 1000085656
Erschienen in Frontiers in physiology
Verlag Frontiers Media SA
Band 9
Heft AUG
Seiten Art.Nr.: 1126
Bemerkung zur Veröffentlichung Gefördert durch den KIT-Publikationsfonds
Vorab online veröffentlicht am 22.08.2018
Schlagwörter ECG; inverse problem; spatio-temporal regularization; basis vectors; body surface potentials; atrial ectopic beats
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