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'Viropore-Membranes' - Talk I: Solid state membrane pores as base for electrochemically driven insertion of bio-nanorings – a “pore-in-pore” membrane preparation approach

Farajollahi, Farid; Altintoprak, Klara; Seidenstücker, Axel; Ziemann, Paul; Plettl, Alfred; Walther, Paul; Marti, Othmar; Wege, Christina

Abstract (englisch):

Nanoporous membranes are of increasing interest for many applications such as molecular filters, biosensors, nanofluidic logic, and energy conversion devices. To meet highest standards e.g. in molecular separation processes, membranes with pores well defined in terms of pore diameter and chemical properties are coercively required. However, the preparation of membranes with narrow pore diameter distributions is still challenging. In the work presented here, we demonstrate a novel “pore-in-pore” approach. The conical pores of a solid state membrane (SSM) template, produced by a multi-step top-down lithography procedure, are used to insert precisely formed bionanorings with exactly defined inner and outer diameters and protein surfaces. The RNA-stabilized porous 'disks' are prepared from natural building blocks of tobacco mosaic virus (TMV) particles and are tailored for the intended insertion and immobilization in the solid pores, to be achieved by means of silica serving as 'bionic glue' (see 'Viropore-Membranes' project talk II, Wege et al. ). The disks consist of a defined number of TMV coat proteins (CPs), have an outer diameter of 18 nm and a central pore with a diameter of 4 nm in the case of natural wild type CPs. ... mehr

Zugehörige Institution(en) am KIT Institut für Funktionelle Grenzflächen (IFG)
Publikationstyp Vortrag
Publikationsdatum 22.03.2018
Sprache Englisch
Identifikator KITopen-ID: 1000086742
HGF-Programm 47.02.06 (POF III, LK 01) Zellpopul.auf Biofunk.Oberflächen IFG
Veranstaltung 4th Euro Bio-inspired Materials (2018), Potsdam, Deutschland, 19.03.2018 – 22.03.2018
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