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The potential of paper-based diagnostics to meet the ASSURED criteria

Smith, Suzanne; Korvink, Jan G. 1; Mager, Dario ORCID iD icon 1; Land, Kevin J.
1 Institut für Mikrostrukturtechnik (IMT), Karlsruher Institut für Technologie (KIT)


Paper-based diagnostics have already revolutionized point-of-care approaches for health and environmental applications, by providing low-cost, disposable tools that can be utilized in remote settings. These devices typically consist of microfluidic, chemical, and biological diagnostic components implemented on paper substrates, towards addressing the ASSURED (Affordable, Sensitive, Specific, User friendly, Rapid and Robust, Equipment free and Deliverable to end users) principles set out by the World Health Organization. Paper-based diagnostics primarily contribute to the affordable, equipment-free, and deliverable-to-end-user aspects. However, additional functionality must be integrated with paper-based diagnostic devices to achieve truly ASSURED solutions. Advances in printed electronics provide a fitting foundation for implementing augmented functionality, while maintaining the affordability and disposability of paper-based diagnostics. This paper reviews the printed functional building blocks that contribute towards achieving this goal, from individual printed electronic components to fully integrated solutions. Important modules for sensing, read-out of results, data processing and communication, and on-board power are explored, and solutions printed on flexible or paper-based substrates for integration with paper-based diagnostics are considered. ... mehr

Verlagsausgabe §
DOI: 10.5445/IR/1000086766
Veröffentlicht am 22.10.2018
DOI: 10.1039/C8RA06132G
Zitationen: 80
Web of Science
Zitationen: 77
Zitationen: 91
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Mikrostrukturtechnik (IMT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2018
Sprache Englisch
Identifikator ISSN: 2046-2069
KITopen-ID: 1000086766
HGF-Programm 43.22.03 (POF III, LK 01) Printed Materials and Systems
Erschienen in RSC Advances
Verlag Royal Society of Chemistry (RSC)
Band 8
Heft 59
Seiten 34012-34034
Bemerkung zur Veröffentlichung Gefördert durch den KIT-Publikationsfonds
Nachgewiesen in Dimensions
Web of Science
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