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Reduction of Antibiotic Resistant Bacteria During Conventional and Advanced Wastewater Treatment, and the Disseminated Loads Released to the Environment

Jäger, Thomas; Hembach, Norman; Elpers, Christian; Wieland, Arne; Alexander, Johannes; Hiller, Christian; Krauter, Gerhard; Schwartz, Thomas

The occurrence of new chemical and microbiological contaminants in the aquatic environment has become an issue of increasing environmental concern. Thus, wastewater treatment plants (WWTPs) play an important part in the distribution of so-called new emerging pathogens and antibiotic resistances. Therefore, the daily loads released by the WWTP were calculated including a model system for the distribution of these loads within the receiving water body. UV-, as well as ozone-treatment in separate or in combination for wastewater treatment were under investigation aiming at the reduction of these loads. Here, the impact of these treatments on the DNA integrity via antibody staining and PCR efficiencies experiments were included. All three facultative pathogenic bacteria [enterococci (23S rRNA), Pseudomonas aeruginosa (ecfX), and Escherichia coli (yccT)] and seven clinically relevant antibiotic resistance genes (ARGs) (mecA (methicillin resistance gene), ctx-M32 (β- lactame resistance gene), ermB (erythromycine resistance gene), blaTEM (β- lactame resistance gene), sul1 (sulfonamide resistance gene), vanA (vancomycin resistance gene), an ... mehr

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Verlagsausgabe §
DOI: 10.5445/IR/1000087101
Veröffentlicht am 31.10.2018
DOI: 10.3389/fmicb.2018.02599
Web of Science
Zitationen: 1
Zugehörige Institution(en) am KIT Institut für Funktionelle Grenzflächen (IFG)
Publikationstyp Zeitschriftenaufsatz
Jahr 2018
Sprache Englisch
Identifikator ISSN: 1664-302X
KITopen-ID: 1000087101
HGF-Programm 47.02.06 (POF III, LK 01)
Erschienen in Frontiers in microbiology
Band 9
Seiten Article No. 2599
Bemerkung zur Veröffentlichung Gefördert durch den KIT-Publikationsfonds
Vorab online veröffentlicht am 30.10.2018
Schlagworte antibiotic resistance, wastewater treatment, ozonation, UV irradiation, DNA damage, qPCR, modeling, daily discharge
Nachgewiesen in Web of Science
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