This paper presents a safe-by design approach developed for enhanced links containing nanomaterials for 3D inkjet printing. Manufactured nanomaterials, like aluminium oxides and zirconium dioxide are increasingly used for additive manufacturing today. However, the impact and interaction of nanomaterials on human health and the environment is widely discussed today. Our approach aims to describe the safe and sustainable use of nanomaterials for 3D links. We rely on well characterized non-toxic nanomaterials, their properties are documented in safety data sheets. In order to identify possible exposure to humans and the environment, we investigate the development of links and their application in the 3D printing process.