Currently, hybrid-electric aircraft are under investigation as one possible solution to reduce the emissions of the aviation industry according to Flightpath 2050 of the European Union. To meet the drive trainʼs requirements on low mass while aiming for highest efficiency, superconducting technologies are regarded as a key enabling technology for drive train powers of several tens of megawatts. Within the German nationally funded project TELOS an exemplary mission profile and the physical measures of a 220-passenger aircraft are used to derive the requirements for a cryogenic-cooled serial hybrid-electric propulsion system. To optimize the total system performance, we subsequently evaluated the superconducting and cryogenic-cooled components by using computationally fast, analytical models. This approach allows quantifying the system performance by using component technologies being available today. In particular, the system performance of geared drive to direct drive propulsion units are compared and the influence of the DC bus voltage and the electric frequencies of the AC circuits on the mass and the efficiency of the drive trains are analysed.