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Addiction Research Consortium: Losing and regaining control over drug intake (ReCoDe)—From trajectories to mechanisms and interventions

Heinz, Andreas; Kiefer, Falk; Smolka, Michael N.; Endrass, Tanja; Beste, Christian; Beck, Anne; Liu, Shuyan; Genauck, Alexander; Romund, Lydia; Banaschewski, Tobias; Bermpohl, Felix; Deserno, Lorenz; Dolan, Raymond J.; Durstewitz, Daniel; Ebner‐Priemer, Ulrich; Flor, Herta; Hansson, Anita C.; Heim, Christine; Hermann, Derik; Kiebel, Stefan; ... mehr

Abstract (englisch):
One of the major risk factors for global death and disability is alcohol, tobacco, and
illicit drug use. While there is increasing knowledge with respect to individual factors
promoting the initiation and maintenance of substance use disorders (SUDs), disease
trajectories involved in losing and regaining control over drug intake (ReCoDe) are
still not well described. Our newly formed German Collaborative Research Centre
(CRC) on ReCoDe has an interdisciplinary approach funded by the German Research
Foundation (DFG) with a 12-year perspective. The main goals of our research consortium
are (i) to identify triggers and modifying factors that longitudinally modulate the
trajectories of losing and regaining control over drug consumption in real life, (ii) to
study underlying behavioral, cognitive, and neurobiological mechanisms, and (iii) to
implicate mechanism-based interventions. These goals will be achieved by: (i) using
mobile health (m-health) tools to longitudinally monitor the effects of triggers (drug
cues, stressors, and priming doses) and modify factors (eg, age, gender, physical activity,
and cognitive control) on drug consumption patterns in real-life conditions and in
... mehr

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DOI: 10.1111/adb.12866
Zitationen: 23
Web of Science
Zitationen: 17
Zugehörige Institution(en) am KIT Institut für Sport und Sportwissenschaft (IfSS)
Publikationstyp Zeitschriftenaufsatz
Publikationsmonat/-jahr 03.2020
Sprache Englisch
Identifikator ISSN: 1355-6215, 1369-1600
KITopen-ID: 1000119407
Erschienen in Addiction biology
Verlag Wiley
Band 25
Heft 2
Seiten Art.-Nr. e12866
Vorab online veröffentlicht am 20.12.2019
Schlagwörter addiction, alternative rewards, animal and computational models, cognitive-behavioral control, craving and relapse, habit formation
Nachgewiesen in Web of Science
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