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Effects of a 16-week multimodal exercise program on gait performance in individuals with dementia: a multicenter randomized controlled trial

Trautwein, Sandra 1; Barisch-Fritz, Bettina ORCID iD icon 1; Scharpf, Andrea 1; Ringhof, Steffen 1; Stein, Thorsten 1; Krell-Roesch, Janina ORCID iD icon 1; Woll, Alexander ORCID iD icon 1
1 Institut für Sport und Sportwissenschaft (IfSS), Karlsruher Institut für Technologie (KIT)


There is a high prevalence of gait impairments in individuals with dementia (IWD). Gait impairments are associated with increased risk of falls, disability, and economic burden for health care systems. Only few studies have investigated the effectiveness of physical activity on gait performance in IWD, reporting promising but inconsistent results. Thus, this study aimed to investigate the effectiveness of a multimodal exercise program (MEP) on gait performance in IWD.
In this parallel-group randomized controlled trial, we enrolled 319 IWD of mild to moderate severity, living in care facilities, aged ≥ 65 years, and being able to walk at least 10 m. The control group (n = 118) received conventional treatment, whereas the intervention group (n = 201) additionally participated in a 16-week MEP specifically tailored to IWD. We examined the effects of the MEP on spatiotemporal gait parameters and dual task costs by using the gait analysis system GAITRite. Additionally, we compared characteristics between positive, non-, and negative responders, and investigated the impact of changes in underlying motor and cognitive performance in the intervention group by conducting multiple regression analyses.
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Verlagsausgabe §
DOI: 10.5445/IR/1000121903
Veröffentlicht am 21.07.2020
DOI: 10.1186/s12877-020-01635-3
Zitationen: 12
Web of Science
Zitationen: 12
Zitationen: 13
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Sport und Sportwissenschaft (IfSS)
Publikationstyp Zeitschriftenaufsatz
Publikationsmonat/-jahr 12.2020
Sprache Englisch
Identifikator ISSN: 1471-2318
KITopen-ID: 1000121903
Erschienen in BMC geriatrics
Verlag Springer Fachmedien Wiesbaden
Band 20
Heft 1
Seiten Article no: 245
Vorab online veröffentlicht am 16.07.2020
Schlagwörter Physical activity, Neurodegenerative disorder, Walking, Physical functional performance, Cognition, Dual task
Nachgewiesen in Dimensions
Web of Science
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