The purpose of this study was the biomechanical inter-leg evaluation in three team handball-specific side-cutting maneuvers. This should help to gain a better understanding how different movement executions potentially produce harmful demands to one or both knee joints. Therefore, eight competitive handball player performed the three most common side-cutting maneuvers to the right side (sode-cuttingmaneuver was performed with alternating or simultaneous steps) in a game-like setting in a movment laboratory. Movement data were collected with a 3D motion capture system and two linked 3D force plates. The analysis of the side-cutting maneuvers revealed increased vertical and medio-lateral ground reaction force components on the left leg, which initiated the side-cutting maneuver. The peak knee abduction moments in the weight acceptance phase did not differ between the left and the right leg in all three side-cutting maneuvers. However, higher peak knee valgus occurred at the left leg, wich increased with increasing stance time. The results of this study indicate that during the performance of handball-specific side-cutting to the right, the left knee joint has a greater risk to get injured. ... mehrConsequently, athletes and coaches should place special focus on the movement execution of the cutting initiating leg to reduce the risk of knee injuries. Furthermore, leg explosive strength and core stability should be in major focus in training exercises to prepare the athlete for the demands in such high intensity movements.