The IoT solutions for health informatics are suffering from restriction of using one frequency which makes the network is unable to communicate via different frequencies. Also, this limitation of using a single frequency fixes a single communication range between nodes without the capability to vary the covering rang. This could consume high power if the system has to transmit data on long distance due to the need to use signal repeater node/s. This paper reports the development of a new heterogeneous design of IoT network via unsymmetrical frequencies in order to sense, process, exchange and visualize two vital signs. The sensing and processing phases are performed via a convenient design of noninvasive vital data acquisition nods. These data acquisition nodes of vital signs are integrated into an embedded system with the IoT nodes in order to provide effective, accurate and real-time health monitoring for vital signs. The design of IoT broker node enables real-time analysis and concatenation of two vital signs. In addition, the broker facilitates the communication between nodes to each other over multi-frequencies in order to cover variant distances and thus to optimize the usage of power. ... mehrMoreover, the proposed software of the IoT broker is able to address run-time issues of network nodes in real time without the need to reset the whole network.