n the present study, the quantity, duration and intensity of heat stress events in Germany as well as their future change and relation with weather types were investigated. A small ensemble of regional climate simulations with the regional climate model (RCM) COSMO-CLM driven by four general circulation models (GCMs) was used to calculate the Universal Thermal Climate Index (UTCI); the UTCI is a well-accepted thermal comfort index which we use here to quantify thermal stress. The variables entering the UTCI were bias corrected with a method that preserves their interdependencies. The projected climate changes cause a significant increase of both the mean UTCI and the number, duration and intensity of heat stress events between the control period (1981–2000) and the projection period (2031–2050). The projected future hourly frequency distribution of the UTCI at a location can be described by a shift to higher UTCI values with an almost constant shape of distribution. The investigations of the projected changes in weather types show no significant changes between the periods covered, with a few exceptions. An exception concerning heat stress events is the increase of summer anticyclonic weather types. ... mehrAlthough more anticyclonic weather types in summer lead to an increase in heat stress events, they are not the primary cause of the projected increases. Rather, it turns out that the characteristics of the air masses associated with the weather types change towards warmer and more humid conditions.