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Geodesic length measurement in medical images: Effect of the discretization by the camera chip and quantitative assessment of error reduction methods

Naber, Ady; Berwanger, Daniel; Nahm, Werner

Abstract:
After interventions such as bypass surgeries the vascular function is checked qualitatively and remotely by observing the blood dynamics inside the vessel via Fluorescence Angiography. This state-of-the-art method has to be improved by introducing a quantitatively measured blood flow. Previous approaches show that the measured blood flow cannot be easily calibrated against a gold standard reference. In order to systematically address the possible sources of error, we investigated the error in geodesic length measurement caused by spatial discretization on the camera chip. We used an in-silico vessel segmentation model based on mathematical functions as a ground truth for the length of vessel-like anatomical structures in the continuous space. Discretization errors for the chosen models were determined in a typical magnitude of 6%. Since this length error would propagate to an unacceptable error in blood flow measurement, counteractions need to be developed. Therefore, different methods for the centerline extraction and spatial interpolation have been tested and compared against their performance in reducing the discretization error in length measurement by re-continualization. ... mehr

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Verlagsausgabe §
DOI: 10.5445/IR/1000125432
Veröffentlicht am 29.10.2020
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Biomedizinische Technik (IBT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2020
Sprache Englisch
Identifikator ISSN: 2304-6732
KITopen-ID: 1000125432
Erschienen in Photonics
Band 7
Heft 3
Seiten Art.-Nr.: 70
Vorab online veröffentlicht am 05.09.2020
Schlagwörter length measurement, discretization error, centerline, spatial interpolation, blood flow
Nachgewiesen in Scopus
Web of Science
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