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Teaching indicators to unravel the kinetic features of host-guest inclusion complexes

Prabodh, Amrutha; Sinn, Stephan; Grimm, Laura; Miskolczy, Z.; Megyesi, M.; Biczók, L.; Bräse, Stefan; Biedermann, Frank

Both thermodynamic and kinetic insights are needed for a proper analysis of association and dissociation processes of host–guest interactions. However, kinetic descriptions of supramolecular systems are scarce in the literature because suitable experimental protocols are lacking. We introduce here three time-resolved methods that allow for convenient determination of kinetic rate constants of spectroscopically silent or even insoluble guests with the macrocyclic cucurbit[n]uril family and human serum albumin (HSA) protein as representative hosts.

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Verlagsausgabe §
DOI: 10.5445/IR/1000125809
Veröffentlicht am 09.11.2020
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Organische Chemie (IOC)
Institut für Nanotechnologie (INT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2020
Sprache Englisch
Identifikator ISSN: 0009-241X, 0022-4936, 1359-7345, 1364-548X, 2050-5620, 2050-5639
KITopen-ID: 1000125809
Erschienen in Chemical communications
Band 56
Heft 82
Seiten 12327-12330
Nachgewiesen in Web of Science
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