The detachment of particle structures from single fibres in gas flow has been investigated only for inert particle structures yet. This study investigates the detachment of particle structures containing reactive components. These reactive components disappear during the reaction and enhance detachment at low flow velocities. Soot was used as the reactive component and glass spheres as the inert component of the particle structure. The soot disappears due to combustion with oxygen leaving only the glass spheres on the fibre. Without reaction, the detachment phenomenon was observed at superficial flow velocities above 1.9 m/s and with reaction at 0.5 m/s. This shows that reacting and disappearing components of the particle structure can enhance detachment.