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Controlling Geometry and Flow Through Bacterial Bridges on Patterned Lubricant‐Infused Surfaces (pLIS)

Lei, Wenxi; Krolla, Peter; Schwartz, Thomas; Levkin, Pavel A.

Abstract:
Spatial control of bacteria and biofilms on surfaces is necessary to understand the biofilm formation and the social interactions between bacterial communities, which could provide useful hints to study the biofilm‐involved diseases. Here patterned lubricant‐infused surfaces (pLIS) are utilized to fabricate connective structures named “bacterial bridges” between bacterial colonies of Pseudomonas aeruginosa by a simple dewetting method. It is demonstrated that the bacteria attached to hydrophilic areas and bacteria precipitated on lubricant infused borders both contribute to the formation of bacterial bridges. The geometry and distribution of bridges can be controlled using predesigned superhydrophobic–hydrophilic patterns. It is demonstrated that bacterial bridges connecting bacteria colonies act as bio‐microfluidic channels and can transport liquids, nutrients, and antibacterial substances between neighboring bacteria clusters. Thus, bacterial bridges can be used to study formation, spreading, and development of bacterial colonies, and communication within and between isolated biofilms.

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Verlagsausgabe §
DOI: 10.5445/IR/1000127064
Veröffentlicht am 01.12.2020
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Biologische und Chemische Systeme (IBCS)
Institut für Funktionelle Grenzflächen (IFG)
Institut für Organische Chemie (IOC)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2020
Sprache Englisch
Identifikator ISSN: 1613-6810, 1613-6829
KITopen-ID: 1000127064
HGF-Programm 47.02.06 (POF III, LK 01) Zellpopul.auf Biofunk.Oberflächen IFG
Weitere HGF-Programme 47.01.01 (POF III, LK 01) Biol.Netzwerke u.Synth.Regulat. ITG+ITC
Erschienen in Small
Verlag Wiley
Seiten Art.-Nr.: 2004575
Vorab online veröffentlicht am 20.11.2020
Nachgewiesen in Web of Science
Scopus
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