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On enhanced sensing of chiral molecules in optical cavities

Scott, Philip; Garcia-Santiago, Xavier; Beutel, Dominik; Rockstuhl, Carsten; Wegener, Martin; Fernandez-Corbaton, Ivan

Abstract:
The differential response of chiral molecules to incident left- and right-handed circularly polarized light is used for sensing the handedness of molecules. Currently, significant effort is directed toward enhancing weak differential signals from the molecules, with the goal of extending the capabilities of chiral spectrometers to lower molecular concentrations or small analyte volumes. Previously, optical cavities for enhancing vibrational circular dichroism have been introduced. Their enhancements are mediated by helicity-preserving cavity modes which maintain the handedness of light due to their degenerate TE and TM components. In this article, we simplify the design of the cavity and numerically compare it with the previous one using an improved model for the response of chiral molecules. We use parameters of molecular resonances to show that the cavities are capable of bringing the vibrational circular dichroism signal over the detection threshold of typical spectrometers for concentrations that are one to three orders of magnitude smaller than those needed without the cavities, for a fixed analyte volume. Frequency resolutions of current spectrometers result in enhancements of more than one order (two orders) of magnitude for the new (previous) design. ... mehr


Verlagsausgabe §
DOI: 10.5445/IR/1000128106
Veröffentlicht am 20.12.2021
Originalveröffentlichung
DOI: 10.1063/5.0025006
Scopus
Zitationen: 3
Web of Science
Zitationen: 3
Dimensions
Zitationen: 3
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Angewandte Physik (APH)
Institut für Nanotechnologie (INT)
Institut für Theoretische Festkörperphysik (TFP)
Publikationstyp Zeitschriftenaufsatz
Publikationsdatum 17.12.2020
Sprache Englisch
Identifikator ISSN: 1931-9401
KITopen-ID: 1000128106
HGF-Programm 43.23.01 (POF III, LK 01) Advanced Optical Lithography+Microscopy
Erschienen in Applied physics reviews
Verlag American Institute of Physics (AIP)
Band 7
Heft 4
Seiten Art.Nr. 041413
Nachgewiesen in Dimensions
Web of Science
Scopus
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