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The influence of strut-connectors in coronary stents: A comparison of numerical simulations and μPIV measurements

Melzer, Helena-Sophie; Ahrens, Ralf 1; Guber, Andreas E. 1; Dohse, Jakob
1 Institut für Mikrostrukturtechnik (IMT), Karlsruher Institut für Technologie (KIT)

Abstract:
This paper discusses the influence of different designs of strut-connectors of stents by numerical flow simulations and flow examinations using micro particle image velocimetry (μPIV). Many studies have shown that there is a correlation between the hemodynamics after stent implanta-tion and the cause of biological responses like thrombosis and the in-stent restenosis. Recirculation areas may occur through a stent, which are considered to be the cause of these clinical complications. In this study, three different coronary stent designs are investigated and the hemodynamic effects from the different designs is presented. The study focuses on the design of the strut-connectors that connect two struts. Numerical simulations were performed to evaluate various flow features like recirculation zones, velocity profiles and wall shear stress (WSS) patterns. To verify the numerical results μPIV-measurements were performed. It could be shown that the alignment in the main stream of the connectors influences the size and number of recirculation zones.


Verlagsausgabe §
DOI: 10.5445/IR/1000129286
Veröffentlicht am 04.02.2021
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Mikrostrukturtechnik (IMT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2020
Sprache Englisch
Identifikator ISSN: 2364-5504
KITopen-ID: 1000129286
HGF-Programm 47.02.07 (POF III, LK 01) Zellpopul.auf Biofunk.Oberflächen IMT
Erschienen in Current directions in biomedical engineering
Verlag De Gruyter
Band 6
Heft 3
Seiten 392-295
Vorab online veröffentlicht am 26.11.2020
Schlagwörter Stents, Strut-Connectors, Thrombosis, In-Stent-Restenosis, Computational fluid dynamics, Micro-PIV, Coronary heart disease
Nachgewiesen in Dimensions
Scopus
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