A search for the production of Dark Matter in hadronic mono-top signatures using data recorded by the CMS experiment in the years from 2016 to 2018 is presented. First, the analysis strategy is defined relying on the existence of large missing transverse momentum and a large-radius jet. The underlying theoretical model is then studied in order to validate the analysis strategy. Consequently, the modeling of the production of single vector bosons in association with additional jets is studied in detail because of its importance regarding the background model of this analysis. Corrections based on available state-of-the-art theoretical calculations are derived in order to improve the modeling of the aforementioned processes and these corrections are compared to alternative corrections based on Monte Carlo simulation. Next, the data analysis and its technical details are explained. Then, a statistical model is built estimating the major background processes utilizing data from control regions. Finally, a statistical hypothesis test combined with parameter estimation is performed in order to search for possible signal contributions in data. ... mehrNo significant signal contributions were found. Therefore, parameter ranges of the used theoretical signal model were excluded.