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Monte-Carlo Simulations of Soft Matter Using SIMONA: A Review of Recent Applications

Penaloza-Amion, Montserrat; Sedghamiz, Elaheh; Kozlowska, Mariana; Degitz, Carl; Possel, Clemens; Wenzel, Wolfgang

Abstract:
Molecular simulations such as Molecular Dynamics (MD) and Monte Carlo (MC) have gained increasing importance in the explanation of various physicochemical and biochemical phenomena in soft matter and help elucidate processes that often cannot be understood by experimental techniques alone. While there is a large number of computational studies and developments in MD, MC simulations are less widely used, but they offer a powerful alternative approach to explore the potential energy surface of complex systems in a way that is not feasible for atomistic MD, which still remains fundamentally constrained by the femtosecond timestep, limiting investigations of many essential processes. This paper provides a review of the current developments of a MC based code, SIMONA, which is an efficient and versatile tool to perform large-scale conformational sampling of different kinds of (macro)molecules. We provide an overview of the approach, and an application to soft-matter problems, such as protocols for protein and polymer folding, physical vapor deposition of functional organic molecules and complex oligomer modeling. SIMONA offers solutions to different levels of programming expertise (basic, expert and developer level) through the usage of a designed Graphical Interface pre-processor, a convenient coding environment using XML and the development of new algorithms using Python/C++. ... mehr

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Verlagsausgabe §
DOI: 10.5445/IR/1000131885
Veröffentlicht am 30.04.2021
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Nanotechnologie (INT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2021
Sprache Englisch
Identifikator ISSN: 2296-424X
KITopen-ID: 1000131885
Erschienen in Frontiers in Physics
Verlag Frontiers Media
Band 9
Seiten Art.-Nr.: 635959
Nachgewiesen in Scopus
Web of Science
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