KIT | KIT-Bibliothek | Impressum | Datenschutz

Influence of Hydrophilic Surfactants on the W1–W2 Coalescence in Double Emulsion Systems Investigated by Single Droplet Experiments

Leister, Nico ORCID iD icon; Karbstein, Heike P.

Abstract:

Double emulsions are a promising formulation for encapsulation and targeted release in pharmaceutics, cosmetics and food. An inner water phase is dispersed in an oil phase, which is again emulsified in a second water phase. The encapsulated inner water phase can be released via diffusion or via coalescence, neither of which is desired during storage but might be intended during application. The two interfaces in a double emulsion are stabilized by a hydrophilic and a lipophilic surfactant, to prevent the coalescence of the outer and the inner emulsion, respectively. This study focuses on the influence of the hydrophilic surfactant on the release of inner water or actives encapsulated therein via coalescence of the inner water droplet with the outer O–W2 interface. Since coalescence and diffusion are difficult to distinguish in double emulsions, single-droplet experiments were used to quantify differences in the stability of inner droplets. Different lipophilic (PGPH and PEG-30 dipolyhydroxylstearate) and hydrophilic surfactants (ethoxylates, SDS and polymeric) were used and resulted in huge differences in stability. A drastic decrease in stability was found for some combinations, while other combinations resulted in inner droplets that could withstand coalescence longer. ... mehr


Verlagsausgabe §
DOI: 10.5445/IR/1000132146
Originalveröffentlichung
DOI: 10.3390/colloids5020021
Scopus
Zitationen: 12
Dimensions
Zitationen: 13
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Bio- und Lebensmitteltechnik (BLT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2021
Sprache Englisch
Identifikator ISSN: 2504-5377
KITopen-ID: 1000132146
Erschienen in Colloids and Interfaces
Verlag MDPI
Band 5
Heft 2
Seiten Art. Nr.: 21
Bemerkung zur Veröffentlichung Gefördert durch den KIT-Publikationsfonds
Vorab online veröffentlicht am 08.04.2021
Schlagwörter encapsulation; interfacial properties; controlled release; surfactant interaction; diffusion and coalescence time analyzer; DCTA; ethoxylates; SDS; PGPR
Nachgewiesen in Dimensions
Scopus
KIT – Die Forschungsuniversität in der Helmholtz-Gemeinschaft
KITopen Landing Page