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Continuous size fractionation of magnetic nanoparticles by using simulated moving bed chromatography

Arlt, Carsten-Rene 1; Brekel, Dominik 1; Neumann, Stefan; Rafaja, David; Franzreb, Matthias 1
1 Institut für Funktionelle Grenzflächen (IFG), Karlsruher Institut für Technologie (KIT)

The size fractionation of magnetic nanoparticles is a technical problem, which until today can only be solved with great effort. Nevertheless, there is an important demand for nanoparticles with sharp size distributions, for example for medical technology or sensor technology. Using magnetic chromatography, we show a promising method for fractionation of magnetic nanoparticles with respect to their size and/or magnetic properties. This was achieved by passing magnetic nanoparticles through a packed bed of fine steel spheres with which they interact magnetically because single domain ferro-/ferrimagnetic nanoparticles show a spontaneous magnetization. Since the strength of this interaction is related to particle size, the principle is suitable for size fractionation. This concept was transferred into a continuous process in this work using a so-called simulated moving bed chromatography. Applying a suspension of magnetic nanoparticles within a size range from 20 to 120 nm, the process showed a separation sharpness of up to 0.52 with recovery rates of 100%. The continuous feed stream of magnetic nanoparticles could be fractionated with a space-time-yield of up to 5 mg/(L·min). ... mehr

Verlagsausgabe §
DOI: 10.5445/IR/1000133586
Veröffentlicht am 03.06.2021
DOI: 10.1007/s11705-021-2040-3
Zitationen: 1
Zitationen: 1
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Funktionelle Grenzflächen (IFG)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2021
Sprache Englisch
Identifikator ISSN: 2095-0179, 1673-7369, 1673-7474, 2095-0187
KITopen-ID: 1000133586
HGF-Programm 43.33.11 (POF IV, LK 01) Adaptive and Bioinstructive Materials Systems
Erschienen in Frontiers of Chemical Science and Engineering
Verlag Springer Verlag
Band 15
Heft 5
Seiten 1346–1355
Nachgewiesen in Web of Science
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