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Piezoelectric titanium based microfluidic pump and valves for implantable medical applications

Bußmann, Agnes Beate ORCID iD icon 1; Durasiewicz, Claudia Patricia; Kibler, Sebastian Heinrich Alexander; Wald, Christian Klaus
1 Karlsruher Institut für Technologie (KIT)


Medical devices often require precise movement of fluids. Automated implants with no need for manual handling improve patient care significantly. However, existing microfluidic devices do not fulfil the necessary specifications of size, safety, hermetic sealing, and artefact free medical imaging, as well as energy efficiency combined with adapted fluidic properties. In this work we designed, manufactured, and experimentally evaluated three piezoelectric microfluidic devices for implant automation: a diaphragm pump, a normally closed valve, and a normally open valve. All devices are made of titanium, minimizing the risk of artefacts in medical imaging. They have similar form factors and use the same actuation method. For the later, a specific mounting process of the piezo actuator enables outstanding fluidic performance during experimental evaluations. The titanium micropumps show a maximal flow of (14 ± 2.2) ml/min and pressure build-up of 75 kPa. The normally closed valve’s leakage rates are extremely low with less than 1 μL/min. Detailed investigations further include the actuator stroke, a lifetime study for normally open valves, and a numerical and experimental evaluation of the normally closed valve’s spring foil. ... mehr

Verlagsausgabe §
DOI: 10.5445/IR/1000135796
Veröffentlicht am 23.07.2021
DOI: 10.1016/j.sna.2021.112649
Zitationen: 29
Web of Science
Zitationen: 20
Zitationen: 25
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Bio- und Lebensmitteltechnik (BLT)
Publikationstyp Zeitschriftenaufsatz
Publikationsmonat/-jahr 06.2021
Sprache Englisch
Identifikator ISSN: 0924-4247
KITopen-ID: 1000135796
Erschienen in Sensors and actuators <Lausanne> / A
Verlag Elsevier
Band 323
Seiten Art.-Nr.: 112649
Schlagwörter Micropump; Microvalve; Titanium; Piezoelectric bending actuator; Microfluidic system; Microfluidic implant
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