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Atrial Flutter Mechanism Detection Using Directed Network Mapping

Vila, M.; Rivolta, M. W.; Luongo, G.; Unger, L. A.; Luik, A.; Gigli, L.; Lombardi, F.; Loewe, A. ORCID iD icon; Sassi, R.


Atrial flutter (AFL) is a common atrial arrhythmia typically characterized by electrical activity propagating around specific anatomical regions. It is usually treated with catheter ablation. However, the identification of rotational activities is not straightforward, and requires an intense effort during the first phase of the electrophysiological (EP) study, i.e., the mapping phase, in which an anatomical 3D model is built and electrograms (EGMs) are recorded. In this study, we modeled the electrical propagation pattern of AFL (measured during mapping) using network theory (NT), a well-known field of research from the computer science domain. The main advantage of NT is the large number of available algorithms that can efficiently analyze the network. Using directed network mapping, we employed a cycle-finding algorithm to detect all cycles in the network, resembling the main propagation pattern of AFL. The method was tested on two subjects in sinus rhythm, six in an experimental model of in-silico simulations, and 10 subjects diagnosed with AFL who underwent a catheter ablation. The algorithm correctly detected the electrical propagation of both sinus rhythm cases and in-silico simulations. ... mehr

Verlagsausgabe §
DOI: 10.5445/IR/1000140696
Veröffentlicht am 18.01.2022
DOI: 10.3389/fphys.2021.749635
Zitationen: 3
Web of Science
Zitationen: 2
Zitationen: 3
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Biomedizinische Technik (IBT)
Publikationstyp Zeitschriftenaufsatz
Publikationsdatum 26.10.2021
Sprache Englisch
Identifikator ISSN: 1664-042X
KITopen-ID: 1000140696
Erschienen in Frontiers in Physiology
Verlag Frontiers Media SA
Band 12
Seiten Art.Nr. 749635
Schlagwörter cardiac arrhythmias, network theory (graphs), atrial flutter, electrograms, catheter ablation
Nachgewiesen in Web of Science
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