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Configurable 3D Printed Microfluidic Multiport Valves with Axial Compression

Diehm, Juliane; Hackert, Verena; Franzreb, Matthias ORCID iD icon

Abstract:

In the last decade, the fabrication of microfluidic chips was revolutionized by 3D printing. It is not only used for rapid prototyping of molds, but also for manufacturing of complex chips and even integrated active parts like pumps and valves, which are essential for many microfluidic applications. The manufacturing of multiport injection valves is of special interest for analytical microfluidic systems, as they can reduce the injection to detection dead volume and thus enhance the resolution and decrease the detection limit. Designs reported so far use radial compression of rotor and stator. However, commercially available nonprinted valves usually feature axial compression, as this allows for adjustable compression and the possibility to integrate additional sealing elements. In this paper, we transfer the axial approach to 3D-printed valves and compare two different printing techniques, as well as six different sealing configurations. The tightness of the system is evaluated with optical examination, weighing, and flow measurements. The developed system shows similar performance to commercial or other 3D-printed valves with no measurable leakage for the static case and leakages below 0.5% in the dynamic case, can be turned automatically with a stepper motor, is easy to scale up, and is transferable to other printing methods and materials without design changes.


Verlagsausgabe §
DOI: 10.5445/IR/1000141666
Veröffentlicht am 08.01.2022
Originalveröffentlichung
DOI: 10.3390/mi12101247
Scopus
Zitationen: 6
Web of Science
Zitationen: 5
Dimensions
Zitationen: 6
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Funktionelle Grenzflächen (IFG)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2021
Sprache Englisch
Identifikator ISSN: 2072-666X
KITopen-ID: 1000141666
HGF-Programm 43.33.11 (POF IV, LK 01) Adaptive and Bioinstructive Materials Systems
Erschienen in Micromachines
Verlag MDPI
Band 12
Heft 10
Seiten 1247
Bemerkung zur Veröffentlichung Gefördert durch den KIT-Publikationsfonds
Vorab online veröffentlicht am 14.10.2021
Schlagwörter rotatory valve; rapid prototyping; polyjetting; digital light processing (DLP); sealing
Nachgewiesen in Dimensions
Scopus
Web of Science
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