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Quantitative assessment of ventricular far field removal techniques for clinical unipolar electrograms

Lorenz, Nick Johannes; Unger, Laura Anna; Luik, Armin; Dössel, Olaf


The incidence of atrial tachycardia steadily increases in industrial nations. During invasive electrophysiological studies, a cathetermeasureselectrograms within the atrium to assist detailed diagnosis and treatment planning. With unipolar and bipolar electrograms, two different acquisition modes are clinically available.Unipolar electrograms have several advantages over bipolarelectrograms. However, unipolar electrograms are more affected by noise and the ventricular far field. Therefore, only bipolar electrograms are typicallyused in clinical settings.A recently published ventricular far field removal technique models the ventricular far field by a set of dipoles and yieldedpromising results in a simulation study.However, the method lacks quantitative clinical validation.Therefore, we adapted thetechnique to clinical needsand applied it todatasetsoftwo patientsusing four different lengths of the removal window.Results were compared quantitatively by a tailored residual error measure.The used method resulted in a median reduction of the ventricular far field by approximately89% using a removal window of optimal length forbothpatients.The results showedthatthe dipole methodprovides an alternative to other VFF removal techniques in clinical practice because itcan reveal AA originally hidden by VFF without leading to a prolongation of the electrophysiological study.

Verlagsausgabe §
DOI: 10.5445/IR/1000141725
Veröffentlicht am 13.01.2022
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Biomedizinische Technik (IBT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2021
Sprache Englisch
Identifikator ISSN: 2364-5504
KITopen-ID: 1000141725
Erschienen in Current Directions in Biomedical Engineering
Verlag De Gruyter
Band 7
Heft 2
Seiten 243-246
Schlagwörter electroanatomic mapping, atrial electrograms, unipolar electrograms, ventricular far fieldremoval
Nachgewiesen in Scopus
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