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Automated vessel centerline extraction and diameter measurement in OCT Angiography

Viertel, Bernhard K. J.; Naber, Ady; Hoffmann, Simon; Berwanger, Daniel; Kessler, Lucy; Khoramnia, Ramin; Nahm, Werner


Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that enables the visualizationof perfused vasculature in vivo. In ophthalmology,it allows the physician to monitor diseases affecting the vascular networks of the retina such as age-related macular degeneration or diabetic retinopathy. Due to the complexity of the vasculature in the retina,it is of interest to automatically extract vascular parameters which describe the condition of the vessels. Suitable parameters could improve the diagnosis and the treatment during the course of therapy.We present an automated algorithm tocompute the diameters of the vessels in en face OCTA images. After segmentingthe images, the vessel centerlinewascomputed using a thinningalgorithm.The centerline wasrefined by detecting invalid pixelssuch as spursandbycontinuing the centerline until the endsof the vessels. Lastly, the diameter wascomputed by dilating a discrete circle at the position of the centerline or by measuring the distance between both borders of the vessels. The developed algorithms were applied to in vivo images of human eyes. ... mehr

Verlagsausgabe §
DOI: 10.5445/IR/1000141727
Veröffentlicht am 13.01.2022
DOI: 10.1515/cdbme-2021-2050
Zitationen: 1
Zitationen: 1
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Biomedizinische Technik (IBT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2021
Sprache Englisch
Identifikator ISSN: 2364-5504
KITopen-ID: 1000141727
Erschienen in Current Directions in Biomedical Engineering
Verlag De Gruyter
Band 7
Heft 2
Seiten 195-198
Schlagwörter OCT angiography,vascular quantification, vesselcenterline, vessel diameter
Nachgewiesen in Dimensions
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