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Fluid dynamics in the human heart: Altered vortex formation and wash-out in mitral regurgitation simulations

Brenneisen, Jochen; Wentzel, Carlo; Karwan, Farokh; Dössel, Olaf; Loewe, Axel ORCID iD icon


Mitral regurgitation alters the flow conditions in the left ventricle. To account for quantitative changes and to investigate the behavior of different flow components, a realistic computational model of the whole human heart was employed in this study. While performing fluid dynamics simulations, a scalar transport equation was solved to analyze vortex formation and ventricular wash-out for different regurgitation severities. Additionally, a particle tracking algorithm was implemented to visualize single components of the blood flow. We confirmed a significantly lowered volume of the direct flow component as well as a higher vorticity in the diseased case.

Verlagsausgabe §
DOI: 10.5445/IR/1000141728
Veröffentlicht am 10.01.2022
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Biomedizinische Technik (IBT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2021
Sprache Englisch
Identifikator ISSN: 2364-5504
KITopen-ID: 1000141728
Erschienen in Current Directions in Biomedical Engineering
Verlag De Gruyter
Band 7
Heft 2
Seiten 199-202
Schlagwörter CFD, fluid dynamics simulation, mitral regurgitation, flow pattern.
Nachgewiesen in Dimensions
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