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Towards Quantitative ICG Angiography: Fluorescence Monte Carlo Multi Cylinder

Hoffmann, Simon; Naber, Ady; Nahm, Werner


Intraoperative blood flow measurement is an effective way to assess the quality of bypass surgery. Flow quantification from indocyanine green (ICG) angiography promises to be an easy, contact-free method. It shows deviations compared to areference. These are given as factor 𝑘, which dependson the vesseldiameter 𝑑. The radiation transport within the vessel while recording the ICG passage might cause this. It is analyzed in silicoto disclose its impact on 𝑘(𝑑). A Fluorescence Monte Carlo Multi Cylinder (FMCMC) model was developed as a static model, assuming homogeneous concentration of ICG. In contrast to published approaches utilizing a Monte Carlo MultiLayer (MCML) model assuming the deepest penetration location within a photon packet’s path to be the fluorescence location, the events aremodeled. Fluorescenceevent modeling, Multi Cylinder geometry and a homogeneous illumination as well as combinations of these were implemented in separate aspect models. Resulting 𝑘(𝑑)were compared to 𝑘(𝑑)from MCML. Deviations in 𝑘(𝑑)derived from FMCMC and MCML in each aspect model were present. The Root Mean Square Error ranges from 6,8% to 36 %, 𝑘(𝑑)also varied comparing the aspect models to each other. ... mehr

Verlagsausgabe §
DOI: 10.5445/IR/1000141731
Veröffentlicht am 10.01.2022
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Biomedizinische Technik (IBT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2021
Sprache Englisch
Identifikator ISSN: 2364-5504
KITopen-ID: 1000141731
Erschienen in Current Directions in Biomedical Engineering
Verlag De Gruyter
Band 7
Heft 2
Seiten 264-267
Schlagwörter Monte Carlo model, ICGangiography,blood flow measurement, intraoperative video processing
Nachgewiesen in Scopus
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