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Investigation on Non-Segmentation Based Algorithms for Microvasculature Quantification in OCTA Images

Abuzer, Amr; Naber, Ady; Hoffmann, Simon; Kessler, Lucy; Khoramnia, Ramin; Nahm, Werner


Optical Coherence Tomography Angiography (OCTA) is an imaging modality that provides three-dimensional information of the retinal microvasculature and therefore promises early diagnosis and sufficient monitoring in ophthalmology. However, there is considerable variability between experts analysing this data. Measures for quantitative assessment of the vasculature need to be developed and established, such as fractal dimension. Fractal dimension can be used to assess the complexity of vessels and has been shown to be independently associated with neovascularization, a symptom of diseases such as diabetic retinopathy. This investigation assessed the performance of three fractal dimension algorithms: Box Counting Dimension (BCD), Information Dimension (ID), and Differential Box Counting (DBC). Two of those, BCD and ID, rely on previous vessel segmentation. Assessment of the added value or disturbance regarding the segmentation step is a second aim of this study. The investigation was performed on a data set composed of 9 in vivo human eyes. ... mehr

Verlagsausgabe §
DOI: 10.5445/IR/1000141732
Veröffentlicht am 10.01.2022
Cover der Publikation
Zugehörige Institution(en) am KIT Institut für Biomedizinische Technik (IBT)
Publikationstyp Zeitschriftenaufsatz
Publikationsjahr 2021
Sprache Englisch
Identifikator ISSN: 2364-5504
KITopen-ID: 1000141732
Erschienen in Current Directions in Biomedical Engineering
Verlag De Gruyter
Band 7
Heft 2
Seiten 247-250
Schlagwörter Differential Box Counting, OCTA images, Fractal Dimensions
Nachgewiesen in Dimensions
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