Catalytic Iodine and Morpholine as Reagent Combination for Hydration of Alkynes via Markovnikov Addition
Abstract:
This work describes the iodine-catalyzed N-methyl morpholine-promoted hydration of alkynes via Markovnikov type addition. The developed protocol provides a direct approach to synthesize methyl ketones under metal-free condition. A series of aromatic alkynes embedded with electron-donating and electron-withdrawing groups were well-investigated to give the corresponding products in good to high yields.
| Zugehörige Institution(en) am KIT | Institut für Photonenforschung und Synchrotronstrahlung (IPS) |
| Publikationstyp | Zeitschriftenaufsatz |
| Publikationsjahr | 2022 |
| Sprache | Englisch |
| Identifikator | ISSN: 0970-7077 KITopen-ID: 1000148454 |
| HGF-Programm | 56.12.11 (POF IV, LK 01) Materials - Quantum, Complex and Functional |
| Erschienen in | Asian journal of chemistry |
| Verlag | Asian Publication Corporation |
| Band | 34 |
| Heft | 6 |
| Seiten | 1592–1596 |
| Vorab online veröffentlicht am | 18.05.2022 |
| Schlagwörter | Hydration, Terminal alkynes, Markovnikov addition, Iodine-catalyzed, Carbonyl compounds. |
| Nachgewiesen in | Dimensions Scopus |